CHOLESTEROL
Cholesterol, a waxy, fatlike substance produced in the liver, contributes to cell membranes, vitamin D, sex and adrenal hormones, bile production, and other metabolic processes. However, in excess, it causes atherosclerosis, or the build up of plaque in artery walls, that can cause a heart attack, stroke, or peripheral artery disease.
High serum cholesterol is associated with consumption of foods high in saturated fat and dietary cholesterol, including eggs, meat, poultry, and dairy foods. Whole grains, beans, soy products, sea vegetables, and other plant quality foods can suppress or lower cholesterol in the blood. Risk of cardiovascular disease is commonly measured by total cholesterol, the ratio of total cholesterol to “good” HDL cholesterol, and various cholesterol fractions. See Beans, Complex Carbohydrates, Heart Disease, High Blood Pressure, Oats, Sesame, Soy Foods, Tarahumara Diet, U.S. Surgeon-General’s Report, Vegetarians, Vitamin B-12, Wakame, Wheat, Whole Grains.
• Pioneer Study Links Diet, Blood Pressure, and Cholesterol - In one of the first studies to show the direct effects of animal food on raising blood pressure, a study of 21 macrobiotic persons by Harvard Medical School researchers found that the addition of 250 grams of beef per day for four weeks to their regular diet of whole grains and vegetables raised serum cholesterol levels 19 percent. Systolic blood pressure also rose significantly. After returning to a low-fat diet, cholesterol and blood pressure values returned to previous levels.
Source: F. M. Sacks et al., “Effects of Ingestion of Meat on Plasma Cholesterol of Vegetarians,” Journal of the American Medical Association 246:640-44, 1981.
• Soy Lowers Cholesterol - Soy protein in tofu, tempeh, and other soy products can significantly lower cholesterol levels in people with moderately high to high levels, according to a review of 38 trial studies. The higher the cholesterol, researchers said, the greater the ability of soy protein to bring it down. The report found that a diet including 47 grams of soy protein a day cut cholesterol levels by an average of 9.3 percent in a month. For those with cholesterols over 300, the count dropped 20 percent. Harmful triglycerides are also blocked by soy protein, the scientists observed.
“Even a 10 to 15 percent reduction in blood cholesterol levels results in a 20 to 30 percent reduction in the risk of coronary heart disease,” said Dr. James W. Anderson of the University of Kentucky and one of the authors of the report. “This has the potential of making a huge impact on American public health.”
Source: Natalie Angier, “Health Benefits from Soy Protein,” New York Times, August 3, 1995.
• Reducing Cholesterol in Children - Top American health officials joined in calling for a low-fat, low-cholesterol diet for everyone over age two to prevent heart disease in later life, not just for adults at risk for heart attacks and other cardiovascular disease. The recommendations, sponsored by a panel convened by the National Heart, Lung and Blood Institute and the Cholesterol Education Program and endorsed by a coalition of forty-two major health and medical organizations, called for the cholesterol testing of all children whose parents or grandparents had heart attacks or other cardiovascular problems, including a parent with blood cholesterol over 240.
The panel called for reductions in fat consumption and for intake of more grains, vegetables, and fruit.
Groups that endorsed the report included the American Medical Association, the American College of Physicians, the American Public Health Association, the U.S. Food and Drug Administration, the U.S. Department of Agriculture, and the U.S. Department of Health and Human Services.
Source: Warren E. Leary, “Cholesterol Tests Are Recommended for a Quarter of Children,” New York Times, April 9, 1991.
• Low-Fat Diet Reduces Cholesterol - In a study of 1,232 men aged 40 to 49 with high cholesterol who were put on a low-fat diet, researchers found a 13 percent reduction in mean total cholesterol levels in comparison to a control group. At the end of 7.5 years, the incidence of heart attack and sudden death was 47 percent lower in the experimental group. The scientists attributed the changes to reduced cigarette smoking and diet.
Source: I. Hjermann, “Effect of Diet and Smoking Intervention on the Incidence of Coronary Heart Disease: Report from the Oslo Study Group of a Randomised Trial in Healthy Men,” Lancet 2:1303-10, 1981.
• Heart Deaths Decline - America’s declining cholesterol levels and change to a diet lower in fat have coincided with a 54 percent decline in heart disease deaths between 1978 and 1990. During this period, the average cholesterol level in adults dropped from 213 milligrams per deciliter of blood to 205, a 4 percent decline, according to figures compiled by the National Center for Health Statistics.
Studies have shown that for every 1 percent drop in cholesterol level, there is almost a 2 to 4 percent drop in coronary heart disease. The proportion of adults with high cholesterol (over 240) fell from 26 percent to 20 percent during this period.
Source: “Study Shows Drop in Cholesterol Levels in U.S.,” Boston Globe, June 16, 1993.
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