Posts Tagged ‘hormone’

Chemicals in food

Wednesday, April 15th, 2009

CHEMICALS
Chemicals in food, the home, the workplace, and the environment have become a hallmark of modern civilization and are a major cause of the modern health and environmental crises. According to U.S. government estimates, 87,000 chemicals are used as industrial wastes, solvents, cleansers, pesticides, food additives, plastics, cosmetics, nutritional supplements, and petroleum byproducts. An estimated 15 percent of Americans suffer from chemical sensitivity, though their sensitivity is often labeled as psychosomatic. See Attention-Deficit Disorder, Environment, Fluoridation, Infectious Diseases, Pesticides, Sewage Sludge, Water.

• Reproductive and Genetic Effects of Chemicals - Chemicals used in industry and agriculture may be responsible for the epidemic of reproductive problems since 1940. Tens of thousands of chemicals have been introduced in the last half century, many of which remain in the environment for generations. Even small amounts can lead to the accumulation of considerable quantities of toxins in human and animal tissues. This can seriously imperil health, reproduction, and fetal development.
Source: “Male Reproductive Health and Environmental Oestrogens,” Lancet 345(8955):933-35, 1995.

• European Report Faults Hormone Disrupters - The European Environmental Agency has confirmed evidence that many synthetic chemicals in the environment “may be threatening normal hormone function in both humans and and wildlife.” The synthetic chemicals can masquerade as hormones and disrupt the delicate cycles in living organisms. For example, snails, mussels, and other molluscs have turned from female to male as a result of exposure to hormone disruptors. Fish, including the Great Lake salmon, have developed both male and female sex organs. Testicular, breast, and prostate cancers in humans have risen dramatically in recent years and may be associated with exposure to chemicals, including laundry detergents, cosmetics, plastics, and soaps. The report upheld Principle 15 of the 1992 Rio Declaration on Environment and Development, known as the precautionary principle, which states that “where there are threats of serious or irreversible damage, lack of full scientific certainty shall not be used as a reason for postponing cost-effective measures to prevent environmental degradation.”
Source: Jennifer Kalnins, “European Report Recognizes Hormone Disruptions,” Alternatives Journal 24(1):4, 1998.

• EPA to Test Thousands of Chemicals for Cancerous and Mutagenic Effects - In 1998, the Environmental Protection Agency announced a massive project to screen thousands of common chemicals, including pesticides, plastics, and cosmetics, for possible carcinogenic and mutagenic effects. The initial test will examine 15,000 chemicals for estrogen and other endocrine-like effects. Known as endocrine disrupters, certain substances in chemicals can mimic or interfere with hormones, causing problems with development, behavior, and reproduction. These have been associated with causing birth defects, low sperm counts, breast cancer, mental impairment, and other disorders. After initial screening, suspects chemicals would be subjected to comprehensive testing on laboratory mammals, birds, amphibians, fish and shrimp.
Source: John H. Cushman, Jr., “EPA to Hunt Dangers in Everyday Products,” New York Times, August 28, 1998.

• Toxic Deception - In a study of the chemical industry, two researchers document how the chemical industry manipulates science, bends the law, and endangers public health. The book also summarizes many studies detailing the abuse of pesticides, toxins, and carcinogens in the food supply, environment, and workplace.
Source: Dan Fagin and Marianne Lavelle, Toxic Deception (Birch Lane Press, 1997.

• Our Stolen Future - Three researchers examine the worldwide threat of PCBs, DDT, and other toxins to the ecosystem, the food supply, and human beings and the threat they pose to fertility, intelligence, and survival.
Source: Theo Colborn, Dianne Dumanoski, and John Peterson Myers, Our Stolen Future (New York: Dutton, 1996).

• Toxic Chemicals in the Deep Ocean - Toxic industrial chemicals have shown up in the tissues of whales that normally feed in the deep waters of the Atlantic Ocean, raising concern about the safety of the ocean’s food chain. Dutch researchers reported that the chemicals, polybrominated compounds that are used as flame retardants in children’s clothing, TV casings, and other products, behave like PCBs and DDT. The chemicals enter the atmosphere and river and sea water as a result of incomplete municipal incineration and eventually find their way into animal and human tissue. The findings are particularly troubling because the whales normally feed at a depth of between 1000 and 3600 feet and hunt in northern waters that are believed to be clean.
Source: Marlise Simons, “Whale Tissue Raises Worry on Toxic Chemicals,” New York Times, August 30, 1998.

Bovine Growth Hormone

Wednesday, April 15th, 2009

BOVINE GROWTH HORMONE
Bovine Growth Hormone (BGH) is a genetically engineered hormone fed to dairy cows to boost milk production. While the FDA approved its use in 1995, health and consumer groups have expressed concerns about its safety and demanded that it be labelled.
Monsanto, the manufacturer, has sued natural foods stores and companies that label its products BGH-free, claiming that such labels unfairly disparage a legal product. A compromise on the issue of labeling was reached for the first time in 1997 when organic food companies in Illinois and Ben & Jerry’s ice cream settled a lawsuit against the state in which natural foods suppliers won the right to explain to consumers that they oppose recombinant BGH and would not use it on their products, though the FDA has found no significant difference between BGH-treated and untreated cows.
About 25 percent of the milk sold in the U.S. is made from cows treated with BGH.

• BGH and Breast Cancer - According to a recent study in Lancet, women with a relatively small increase in blood levels of Insulin-like Growth Factor I (IGF-1), a naturally occurring grown hormone, are up to seven times more likely to develop premenopausal breast cancer than women with lower levels.
Dr. Samuel S. Epstein, an environmental cancer specialist at the University of Illinois, explained that BGH milk is supercharged with high levels of abnormally potent IGF-1, up 10 times the levels in natural milk and over 10 times more potent. IGF-1 resists pasteurization, digestion by stomach enzymes, and is well absorbed across the intestinal wall, he stated.
“The entire nation is currently being subjected to an experiment involving large-scale adulteration of an age-old dietary staple by a poorly characterized and unlabeled biotechnology product. Disturbingly, this experiment benefits only a very small segment of the agriculture industry while providing no matching benefits to consumers. Even more disturbingly it poses major potential public health risks for the entire U.S. population.”
Source: S. Epstein, “Unlabeled Milk from Cows Treated with Biosynthetic Growth Hormones: A Case of Regulatory Abdication,” International Journal of Health Services 26(1): 173-185, 1996; PR Newswire via NewsEdge Corp., June 21, 1998.

• BGH Increases Cancer Risk - In a review of the evidence linking dairy and breast cancer, researchers with the Physicians Committee for Responsible Medicine contend that the FDA’s approval of BHG, genetically engineered bovine growth hormone, was based on faulty assumptions and studies. While the FDA concluded that it did not differ chemically from natural BGH, studies indicate that BGH differs by 1 to 9 animao acids. The FDA also assumed that BGH is not orally active in humans and that its activity is destroyed during pasteurization, both of which have been contradicted by subsequent studies.
“A substantial body of medical evidence provides possible mechanisms by which milk may promote breast cancer,” the physicians conclude. “(1) IGF-1 and estrogens are present in all milk in micromolar to nanomolar concentrations; (2) IGF-1 is not destroyed during milk pasteurization; (3) IGF-1 has been shown to stimulate or initiate growth of human breast cancer cells; (4) IGF-1 acts synergistically with estrogens, which increase its effects even at nonomolar concentrations; (5) BGH increases IGF-1 levels in milk; (6) IGF-1 and BGH can possibly be absorbed intact from the GI gract; (7) IGF-1 can exert local mitogenic tissue effects and be cleaved to exert local mitogenic tissue effects.” While BGH has not been considered to be a danger because subsequent increase in govine milk IGF-1 levels are within the “normal range” based on untreated cows and human breast milk, the physicians assert that the “normal range” could be carcinogenic when milk is ingested regularly over a lifetime. They conclude that milk produced with BGH may increase the risk of cancer.
Source: J. L. Outwater et al., “Dairy Products and Breast Cancer: The IGF-1, Estrogen, and BGH Hypothesis,” Medical Hypotheses 48:453-61, 1997.

• BGH Effects on Cows - Injecting BGH reduces a cow’s life expectancy and increases the risk of disease, contributing to increased use of antibiotics. Increased mastitis results in increased secretion of white blood cells or pus into the milk.
Source: J. Fagan, Genetic Engineering: The Hazards, MIU Press, 1995, p. 113.